Using Patient Derived Tumor Infiltrating Lymphocytes To Treat Metastatic Melanoma

Tumor infiltrating lymphocytes (TIL) are white blood cells that are taken from a patients tumor tissue, expanded and primed (activated) against known melanoma proteins, and injected back into the patient. In an ongoing trial, 50–75% of the patients achieved objective responses with possibly 25–35% being complete responses. I like this personalized approach because it uses a patient’s own cells to target their unique genomic background. This following is a link to a current TIL melanoma trial.
Modified Tumor Infiltrating Lymphocytes for Metastatic Melanoma.

 

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