Amazing Results From ICT-107 Glioblastoma Clinical Trial

ICT-107 is a dendritic cell-based vaccine targeting multiple tumor associated antigens for glioblastoma and is showing an 80.2% overall survival at 2yrs and 55% overall survival at 3yrs, with 38% of patients disease free at 3yrs…compared to a… [Learn More…]

DCVax: Slowing the Progression of Metastatic Prostate Cancer.

Prostate cancer patients whom experience rising PSA levels while on hormone treatment typically progress to metastatic disease on average in about 28-36 weeks. DCVax is a vaccine made from a patient’s own dendritic cells and loaded with a form of… [Learn More…]

JX-594: A Targeted Oncolytic Poxvirus, Followed by Sorafenib in Hepatocellular Carcinoma

JX-594 is a targeted and granulocyte-macrophage colony stimulating factor (GM-CSF) expressing oncolytic poxvirus designed to selectively replicate in and destroy cancer cells through viral oncolysis and tumor-specific immunity. In this trial,… [Learn More…]

NICO Myriad: An Amazing New Surgical Tool!

This amazing new tool allows for minimally invasive brain tumor removal combined with extraction of live tumor samples in order to determine the most effective treatment protocol. I like this tool because it is highly innovative, has a modular… [Learn More…]

PET-MRI: The Benefits Of PET-CT Without The Radiation

PET-MRI is better than PET-CT at showing detailed anatomical information such as angiogenesis. I like this technique because it allows identification of tumors without the use of ionizing radiation, which can be important for repeated scanning to… [Learn More…]

Gamma Knife For Small Recurrent High-Grade Gliomas Following Prior Radical Resection

Gamma Knife utilizes a technique called stereostactic radiosurgery, which uses multiple beams of radiation converging in three dimensions to focus on small volume tumors and permitting intense doses of radiation to be delivered to that volume… [Learn More…]

Using Genomic Data To Improve The Therapeutic Stratification Of Patients

This AML project will increase the use of AML genomic data to improve the therapeutic stratification of patients, thereby leading to more personalized treatment of AML and hopefully, improved outcomes. Personalized Medicine on the Horizon for BC… [Learn More…]

Sorfenib For AML Patients With The FLT3-ITD Mutation

Sorfenib slows the spread of cancer cells by inhibiting angiogenesis (VEGFR-2,-3) as well as growth factor receptors (PDGFR, KIT). Recently, it has been used for AML patients with the FLT3-ITD mutation, the most common mutation in AML patients. I… [Learn More…]

Natural Killer Cell Based Non-Myeloablative Transplantation For Acute Myeloid Leukemia

Non-myeloablative transplantation provides a therapeutic strategy for treating patients with active infection who cannot tolerate conventional myeloablative transplantation using high-dose chemoradiotherapy. Besides having less side effects (due to… [Learn More…]

Itraconazole: An Antifungal Drug That Delays Need For Chemo In Advanced Prostate Cancer

Itraconazole is an antifungal drug commonly used to treat nail fungus. Recent research has shown that it also disrupts a key cancer-initiating pathway and appears to prevent angiogenesis in prostate cancers. I like this approach because it… [Learn More…]