Archives for August 2011

TSC: Improving Brain Cancer Sensitivity To Radiation And Chemotherapy

TSC is a drug that enhances oxygen diffusion into the tumor micro-environment, making treatment-resistant brain tumor cells up to three times more susceptible to standard radiation and chemotherapy treatments. I like this approach because it… [Learn More…]

Using TH-302 And Avastin For Treatment Resistant Glioblastoma

TH-302 is a novel small molecule hypoxia-targeted drug that is selectively activated by the low oxygen conditions believed to be induced in tumors by antiangiogenic therapies. Avastin is a monoclonal antibody that affects tumor vasculature… [Learn More…]

Curcumin Selectively Inhibits Glioblastoma Cell Growth

While this information is not new, this study is more evidence that curcumin regulates key cancer causing genes and pathways and should be a daily addition for anyone with brain cancer. The Curry Spice Curcumin Selectively Inhibits Cancer Cells… [Learn More…]

Celebrex Induces The Expression Of Angiogenesis In Glioma Cell Lines

Celebrex is a non-steroidal anti-inflammatory drug (NSAID) and selective COX-2 inhibitor used in the treatment of osteoarthritis and rheumatoid arthritis. COX-2 expression is linked to increased angiogenesis and a worse prognosis in patients with… [Learn More…]

DCVax: Longer Survival Rates Without The Harsh Side Effects Of Standard Treatments

DCVax is an approach that utilizes a patient’s own dendritic cells and extracts of the patient’s own tumor cells to create a personalized treatment. I like this approach because patients who received DCVax showed a median survival of 3 years,… [Learn More…]